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by PY Pan 2024 Cited by 9In contrast, lamotrigine, a mood stabilizer, has been proven to be effective in preventing depression in patients with bipolar disorder. However The GeneSight Psychotropic test analyzes how your genes may affect your outcomes with medications commonly prescribed to treat depression, anxiety, ADHD, and by M Hopwood Cited by 942Guidelines, depression, bipolar disorder, depressive disorder, mania, mood disorders, Guaiana G, Barbui C and Hotopf M (2024) Amitriptyline for depression. tolfen 2mg Amitriptyline. Drug Information. Common brand names: Elavil. Summary of bipolar disorder. These levels did not improve the effects of imipramine in Tricyclic antidepressants (TCAs) are used to treat depression, bipolar disorder, and other conditions such as chronic pain and insomnia. Heart rhythm disorders and hypotension may occur if you receive a high dosage of amitriptyline. bipolar disorder. schizophrenia. severe liver disease. Screening Patients for Bipolar Disorder A major depressive episode may be the initial presentation of bipolar disorder. It is generally believed (though not established in controlled trials) that treating such an episode with an antidepressant alone may increase the likelihood of precipitation of a mixed/manic episode in patients at risk for
Anthracyclines and some monoclonal antibody-based chemotherapy treatments can be cardiotoxic. These drugs are commonly used to treat breast cancer and lymphomas. An estimated 32,220 new cases of breast cancer of lymphoma are expected in Canada in 2024. 17 It is recognized that not all patients with these cancer types will receive chemotherapy Cardiotoxicity from trastuzumab is largely reversible and therefore characterized as causing type II chemotherapy-related cardiac dysfunction. 13 Doxorubicin is the prototypical example of a type I chemotherapy-related cardiac dysfunction agent and results in irreversible, dose-dependent myocardial damage. In contrast, trastuzumab appears to (See Cardiotoxicity of cancer chemotherapy agents other than ○Exposure to other cardiotoxic cancer therapies – Other cancer We use cookies to enhance your browsing experience, serve personalized ads or content, and analyze our traffic. By clicking Accept All, you consent to our Some drugs currently available for treatment of heart failure with reduced ejection fraction and others with antioxidative effects may hifein INTRODUCTION. Cancer patients receiving chemotherapy have an increased risk of developing cardiovascular complications, and the risk is even greater if there is a known history of heart disease. Among the serious complications that have been reported are: Arrhythmias. Heart failure. Myocardial necrosis causing a dilated cardiomyopathy.
by MA Mourad 2024Chemotherapeutic agents are classified into two types: Type I and Type Il [4,5,6,7]:. Type I: All types of anthracyclines (doxorubicin Cardiotoxicity is a potential adverse effect of a number of antineoplastic drugs. The risk of cardiotoxicity is dependent upon several factors, including the type of chemotherapy agent, administered dose and administration rate (continuous infusion versus bolus) of the drug, advanced or young age, female gender, co-morbidities such as hypertension and pre-existing heart disease, concurrently Drug-induced gene expression profiles can identify potential mechanisms of toxicity. We focus on obtaining signatures for cardiotoxicity of FDA-approved tyrosine kinase inhibitors (TKIs) in human Cardiotoxicity is a well-known side effect of various antineoplastic agents like anthracyclines and 5-fluorouracil chemotherapy agents. Many
